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            <p>Who are the best replacements for the injured <strong>Ismaila Sarr</strong>? Is it too early to invest in <strong>Alexander Isak</strong>? And are Nottingham Forest defenders worth keeping amid concerns over a change in management?</p>
<p>FPL content creator and pundit Holly Shand covers the key Gameweek 4 dilemmas to help Fantasy Football Hub members with their decision-making as Saturday's deadline approaches (September 13).</p>
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<h2>Best Sarr replacements?</h2>
<p>Crystal Palace's Sarr is reportedly out for the next four weeks after picking up a hamstring injury in the 3-0 win against Aston Villa. We await a formal confirmation from <a href="https://www.fantasyfootballhub.co.uk/premier-league-predicted-lineups">Crystal Palace manager Oliver Glasner</a>.</p>
<p>His absence would be unfortunate timing after goals in consecutive games and Sunderland and West Ham up next for the £6.5m midfielder.</p>
<p><strong>Jack Grealish (£6.7m) </strong>is among the best replacements at a similar price point, having delivered four goal involvements from two starts.</p>
<p>It's been a blistering start for the England midfielder at Everton and now there's enticing fixtures upcoming too.</p>
<p>Grealish faces his boyhood club Aston Villa next, before playing in the Merseyside derby in Gameweek 5 and then West Ham in Gameweek 6.</p>
<p>If you've got money in the bank, then an upgrade to Bournemouth's <strong>Antoine Semenyo (£7.4m) </strong>could be another key move.</p>
<p>The Cherries have the perfect blend of form and fixtures, with Semenyo dominating midfielders for shots (10) and big chances (five).</p>
<div id="attachment_74615" style="width: 850px" class="wp-caption aligncenter"><img aria-describedby="caption-attachment-74615" class="size-full wp-image-74615" src="https://cms.fantasyfootballhub.co.uk/wp-content/uploads/2025/09/Grealish-v-Semenyo.jpeg" alt="Jack Grealish v Antoine Semenyo" width="840" height="690" /></p>
<p id="caption-attachment-74615" class="wp-caption-text">Jack Grealish v Antoine Semenyo</p>
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<h2>What justifies using a chip this week?</h2>
<p>I always find the gameweek after an international break particularly challenging to navigate - especially this one so soon after the summer transfer window closed.</p>
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FPL Gameweek 4 Q&A: Best Sarr replacements, is it too early for Isak?

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